Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21924104 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL13189550 | 0.83 | ALOX15 (0.36) | ALOX15HSD17B10ALDH1A1LDHASRR | |
| SCHEMBL19597455 | 0.79 | ALOX15 (0.33) | ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL15832511 | 0.77 | FBP1 (0.33) | ALOX15HSD17B10 | |
| SCHEMBL23904591 | 0.77 | — | — | |
| SCHEMBL2709395 | 0.77 | — | — | |
| SCHEMBL12810918 | 0.75 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL24489498 | 0.74 | KDM4E (0.35) | ALOX15ALDH1A1TGFBR1 | |
| SCHEMBL18530879 | 0.72 | ALOX15 (0.34) | ALOX15HSD17B10 | |
| SCHEMBL24489604 | 0.72 | GRIK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138657-A1 | ARYL SUBSTITUTED OLEFINIC COMPOUNDS AS PDE10A INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-11-10 | — | — | WO | disclosed |