Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633964 | 0.81 | SIRT1 (0.54) | SIRT1MAPTIRAK4TSHRKDM4E | |
| SCHEMBL7701766 | 0.78 | SIRT1 (0.54) | SIRT1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL3077375 | 0.74 | SIRT1 (0.77) | SIRT1MAPTIRAK4TSHRKDM4E | |
| SCHEMBL7688109 | 0.72 | CTNNB1 (0.54) | MAPTIRAK4KDM4EMEN1KMT2A | |
| SCHEMBL21248523 | 0.72 | SIRT1 (0.68) | SIRT1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6629448 | 0.71 | SIRT1 (0.57) | SIRT1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL10764395 | 0.70 | SIRT1 (0.55) | SIRT1MAPTIRAK4TSHRKDM4E | |
| SCHEMBL6632850 | 0.70 | SIRT1 (0.65) | SIRT1MAPTIRAK4TSHRKDM4E | |
| SCHEMBL21248520 | 0.69 | SIRT1 (0.62) | SIRT1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL6633843 | 0.68 | SIRT1 (0.53) | SIRT1MAPTTSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016357-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |