Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.34 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197389 | 0.97 | ILK (0.41) | ILKHTTMAPK8MAPK9MAPK10 | |
| SCHEMBL1005758 | 0.89 | MAPK8 (0.46) | ILKHTTMAPK8MAPK9MAPK10 | |
| SCHEMBL7706938 | 0.88 | KMT2A (0.37) | HTTRAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL7701891 | 0.85 | MAPK8 (0.41) | ILKHTTMAPK8MAPK9MAPK10 | |
| Acetonitrile SCHEMBL7707679 | 0.83 | RAB9A (0.35) | HTTRAB9AALDH1A1KDM4EGAA | |
| SCHEMBL4192495 | 0.81 | KDM4E (0.35) | HTTRAB9AALDH1A1KDM4EGAA | |
| SCHEMBL4192472 | 0.81 | NPC1 (0.46) | MAPK8MAPK9MAPK10RAB9AALDH1A1 | |
| SCHEMBL4187924 | 0.81 | RAB9A (0.36) | HTTRAB9AALDH1A1KDM4EGAA | |
| SCHEMBL4199489 | 0.81 | KMT2A (0.37) | HTTRAB9AALDH1A1KDM4EGAA | |
| SCHEMBL4192595 | 0.80 | MAPK9 (0.36) | ILKHTTMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |