Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187924 | 0.98 | RAB9A (0.36) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL4192273 | 0.88 | MAPK9 (0.39) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL4187935 | 0.88 | ILK (0.38) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL4197422 | 0.88 | SMN1; SMN2 (0.41) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL4186367 | 0.86 | ILK (0.37) | POLBLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL4192472 | 0.86 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL4197304 | 0.86 | ILK (0.40) | RAB9ANPC1SMN1; SMN2POLBLMNA | |
| SCHEMBL4199489 | 0.86 | KMT2A (0.37) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL4190183 | 0.85 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL7706938 | 0.84 | KMT2A (0.37) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |