Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197389 | 0.91 | ILK (0.41) | KMT2ARAB9AMEN1POLBSMN1; SMN2 | |
| SCHEMBL4192472 | 0.90 | NPC1 (0.46) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| Acetonitrile SCHEMBL7707455 | 0.88 | ILK (0.40) | KMT2ARAB9AMEN1POLBSMN1; SMN2 | |
| SCHEMBL4192495 | 0.87 | KDM4E (0.35) | KMT2ARAB9AMEN1NPC1L3MBTL1 | |
| SCHEMBL4192273 | 0.86 | MAPK9 (0.39) | RAB9ANPC1POLBSMN1; SMN2LMNA | |
| SCHEMBL4187924 | 0.86 | RAB9A (0.36) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL6828604 | 0.85 | IDO1 (0.37) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL4199489 | 0.85 | KMT2A (0.37) | KMT2ARAB9AMEN1NPC1POLB | |
| Acetonitrile SCHEMBL7707679 | 0.84 | RAB9A (0.35) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL4186367 | 0.84 | ILK (0.37) | POLBHPGDATMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |