Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705775 | 0.87 | KDM4E (0.49) | ACHEBCHEBACE1CCR3 | |
| SCHEMBL7694829 | 0.85 | HTR2A (0.46) | ACHECCR3HTR2AHTR2CKCNH2 | |
| SCHEMBL7698615 | 0.84 | LTA4H (0.48) | ACHEHTR2A | |
| SCHEMBL7700571 | 0.81 | ACHE (0.42) | ACHECCR3HTR2AHTR2CKCNH2 | |
| SCHEMBL5870777 | 0.80 | ACHE (0.45) | ACHEBCHEBACE1CCR3 | |
| SCHEMBL7695892 | 0.78 | HTR2A (0.45) | ACHECCR3HTR2AHTR2CKCNH2 | |
| SCHEMBL7695908 | 0.76 | HTR2A (0.43) | ACHECCR3HTR2AHTR2CKCNH2 | |
| SCHEMBL7697015 | 0.76 | KCNH2 (0.42) | ACHEHTR2AHTR2CKCNH2 | |
| SCHEMBL7697424 | 0.74 | HTR2A (0.51) | ACHECCR3HTR2AHTR2C | |
| SCHEMBL7698618 | 0.74 | HTR2A (0.41) | ACHEBCHEHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046187-A1 | ANALGESIC DIAZABICYCLO[4.3.0]NONANES | SEPRACOR, INC. (US) | 2002-06-13 | — | — | WO | disclosed |