Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707462 | 0.87 | ACHE (0.44) | ACHEBCHEBACE1CCR3 | |
| SCHEMBL7694829 | 0.80 | HTR2A (0.46) | KDM4EACHECCR3 | |
| SCHEMBL7698615 | 0.78 | LTA4H (0.48) | ACHE | |
| SCHEMBL7700571 | 0.76 | ACHE (0.42) | ACHECCR3 | |
| SCHEMBL7700744 | 0.76 | KCNH2 (0.40) | ACHE | |
| SCHEMBL7705772 | 0.74 | SIGMAR1 (0.41) | — | |
| SCHEMBL7695892 | 0.73 | HTR2A (0.45) | ACHECCR3 | |
| SCHEMBL7695908 | 0.71 | HTR2A (0.43) | ACHECCR3 | |
| SCHEMBL7698618 | 0.71 | HTR2A (0.41) | ACHEBCHE | |
| SCHEMBL17325168 | 0.71 | SLC6A3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046187-A1 | ANALGESIC DIAZABICYCLO[4.3.0]NONANES | SEPRACOR, INC. (US) | 2002-06-13 | — | — | WO | disclosed |