SCHEMBL9513873

SCHEMBL9513873

Cc1cc(NC(C)CCCl)ccc1C=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.34
ALDH1A1 P00352 4/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
MAPT P10636 3/20 0.34
GAA P10253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
HSP90AA1 P07900 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8096813 0.79 ALDH1A1 (0.41) TYRALDH1A1L3MBTL1GAATSHR
SCHEMBL7707476 0.76 ALDH1A1 (0.42) TYRALDH1A1L3MBTL1MAPTTSHR
SCHEMBL2766868 0.70 ALDH1A1 (0.45) TYRALDH1A1MAPTTSHRSMN1; SMN2
SCHEMBL9818635 0.70 CA12 (0.51) TYRALDH1A1MAPTNPSR1HTT
SCHEMBL6554556 0.69 ALDH1A1 (0.41) TYRALDH1A1MAPTGAAHTT
SCHEMBL28175286 0.69 ALDH1A1 (0.38) TYRALDH1A1L3MBTL1MAPTGAA
SCHEMBL11832958 0.69 ALDH1A1 (0.35) TYRALDH1A1L3MBTL1
SCHEMBL10395364 0.66 ALDH1A1 (0.45) ALDH1A1L3MBTL1MAPTGAANPSR1
SCHEMBL30790705 0.66 HTT (0.46) TYRALDH1A1L3MBTL1MAPTHTT
SCHEMBL7251917 0.66 ALDH1A1 (0.51) ALDH1A1L3MBTL1MAPTGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412101-B1 NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM EASTMAN KODAK CO (US) 1993-10-27 EP disclosed
US-5086161-A Ultraviolet radiation screening food packaging EASTMAN KODAK COMPANY (US) 1992-02-04 US disclosed
US-5075491-A Ultraviolet radiation absorbers EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0412101-A1 NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM. EASTMAN KODAK CO (US) 1991-02-13 EP disclosed
US-4958043-A Novel methine compounds, polymers containing them and formed articles therefrom EASTMAN KODAK COMPANY (US) 1990-09-18 US disclosed