Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 4/20 | 0.37 |
| ▸ | ADH1C | P00326 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646285 | 0.89 | EPHX1 (0.38) | TSHRHPGDADH1AADH1C | |
| SCHEMBL973483 | 0.81 | HSD11B1 (0.37) | TSHRHPGDADH1AADH1CHSD11B1 | |
| SCHEMBL6914582 | 0.80 | ADH1A (0.40) | TSHRHPGDADH1AADH1CALDH1A1 | |
| SCHEMBL11135152 | 0.77 | HSD11B1 (0.35) | TSHRHPGDADH1AADH1CHSD11B1 | |
| SCHEMBL6932731 | 0.77 | HSD11B1 (0.39) | TSHRHPGDADH1AADH1CHSD11B1 | |
| SCHEMBL28490982 | 0.76 | LMNA (0.40) | ADH1AADH1CHSD11B1ALDH1A1KDM4E | |
| SCHEMBL5547582 | 0.76 | ADH1A (0.37) | ADH1AADH1CHSD11B1ALDH1A1KDM4E | |
| SCHEMBL28949799 | 0.72 | HSD11B1 (0.35) | ADH1AHSD11B1ALDH1A1KDM4ENPC1 | |
| SCHEMBL4453296 | 0.71 | TSHR (0.42) | TSHRADH1AADH1CALDH1A1KDM4E | |
| SCHEMBL29046352 | 0.70 | NAAA (0.57) | L3MBTL1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039902-B | Aminoalcohol derivatives | ASTELLAS PHARMA INC | 2010-11-10 | — | — | CN | disclosed |
| CN-101061092-A | Niacin receptor agonists, compositions containing such compounds and methods of treatment | MERCK & CO INC (US) | 2007-10-24 | — | — | CN | disclosed |
| CN-101039902-A | Aminoalcohol derivatives | ASTELLAS PHARMA INC (JP) | 2007-09-19 | — | — | CN | disclosed |
| US-6361940-B1 | IMMOBILIZATION; GENETIC ENGINEERING | QIAGEN GENOMICS, INC. | 2002-03-26 | — | — | US | disclosed |
| EP-0958378-A2 | COMPOSITIONS AND METHODS FOR ENHANCING HYBRIDIZATION SPECIFICITY | Rapigene, Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0952228-A2 | Compositions and methods for enhancing hybridization specificity | Rapigene, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998013527-A2 | COMPOSITIONS AND METHODS FOR ENHANCING HYBRIDIZATION SPECIFICITY | RAPIGENE, INC. (US) | 1998-04-02 | — | — | WO | disclosed |
| US-4107432-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4058661-A | 7-Diacyl cephalosporins | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | disclosed |