SCHEMBL7707639

SCHEMBL7707639

CC=C(NC1CC(C)(C)NC(C)(C)C1)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
RECQL P46063 1/20 0.41
POLB P06746 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
MEN1 O00255 1/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40
EZH2 Q15910 3/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5062108 0.81 GAA (0.48) GAARECQLPOLBL3MBTL1ATM
SCHEMBL7707530 0.74 NAAA (0.41) GAARECQLPOLBL3MBTL1ATM
SCHEMBL10525290 0.70 RECQL (0.57) GAARECQLPOLBL3MBTL1ATM
SCHEMBL3295977 0.70 RECQL (0.57) GAARECQLPOLBL3MBTL1ATM
SCHEMBL8944709 0.70 ATM (0.50) GAARECQLPOLBL3MBTL1ATM
SCHEMBL108538 0.69 RECQL (0.47) GAARECQLPOLBL3MBTL1ATM
SCHEMBL9503903 0.69 POLB (0.50) GAARECQLPOLBL3MBTL1ATM
SCHEMBL108540 0.69 RECQL (0.47) GAARECQLPOLBL3MBTL1ATM
SCHEMBL28402532 0.69 POLB (0.57) GAARECQLPOLBL3MBTL1ATM
SCHEMBL77511 0.69 RECQL (0.55) GAARECQLPOLBL3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6353044-B1 PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) 2002-03-05 US claimed
US-6353044-B1 PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) 2002-03-05 US disclosed