Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190547 | 0.92 | MAPK9 (0.39) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL4193807 | 0.87 | PTGS1 (0.35) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL4197491 | 0.87 | CYP2D6 (0.38) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL5613992 | 0.86 | PTGS1 (0.36) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL4203404 | 0.85 | PTGS1 (0.36) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL4192595 | 0.85 | MAPK9 (0.36) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL4192500 | 0.85 | NAAA (0.42) | NAAAPTGS1PTGS2MAPK9MAPK10 | |
| SCHEMBL4197321 | 0.84 | RAB9A (0.49) | PTGS1PTGS2MAPK9MAPK10MEN1 | |
| SCHEMBL5614066 | 0.84 | MAPK8 (0.42) | MAPK9MAPK10MEN1KMT2ANPC1 | |
| SCHEMBL4197270 | 0.83 | PTGS1 (0.36) | PTGS1PTGS2MAPK9MAPK10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |