Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL7707450 | 0.97 | MAPK9 (0.38) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL5613992 | 0.94 | PTGS1 (0.36) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL4203404 | 0.93 | PTGS1 (0.36) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL4197321 | 0.92 | RAB9A (0.49) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL7707665 | 0.92 | NAAA (0.39) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL7707443 | 0.91 | RAB9A (0.44) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL4192595 | 0.91 | MAPK9 (0.36) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL7710188 | 0.91 | LMNA (0.40) | MAPK9MAPK10MEN1KMT2ANPC1 | |
| SCHEMBL4197270 | 0.89 | PTGS1 (0.36) | MAPK9MAPK10PTGS1PTGS2MEN1 | |
| SCHEMBL4197491 | 0.89 | CYP2D6 (0.38) | MAPK9MAPK10PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |
| WO-2006104983-A1 | THERAPEUTIC METHODS FOR TYPE I DIABETES | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2006-10-05 | — | — | WO | disclosed |