Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCRL2 | O00421 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707353 | 1.00 | CCRL2 (0.41) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| Hydrochloric Acid SCHEMBL6956256 | 0.99 | CCRL2 (0.40) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| SCHEMBL6964977 | 0.85 | ADRA1A (0.43) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| SCHEMBL6964976 | 0.81 | KDM4E (0.44) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| Hydrochloric Acid SCHEMBL6956254 | 0.80 | KDM4E (0.43) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| SCHEMBL7968202 | 0.79 | ADRA1A (0.36) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| SCHEMBL8005731 | 0.78 | C5AR1 (0.41) | DRD4GRM2PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL7955138 | 0.78 | KDM1A (0.43) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| Hydrochloric Acid SCHEMBL6961572 | 0.78 | KDM1A (0.43) | CCRL2CCR2KCNH2ADRA1ADRD4 | |
| SCHEMBL29580963 | 0.77 | ADRA1A (0.49) | ADRA1ADRD4GRM2PROKR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358959-B1 | FOR THERAPY OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2002-03-19 | — | — | US | disclosed |