Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997020 | 1.00 | ALOX5 (0.41) | ALOX5KDM4EFDPSENPP2 | |
| SCHEMBL6992552 | 0.77 | ALOX5 (0.49) | ALOX5KDM4E | |
| SCHEMBL7002017 | 0.76 | ABL1 (0.35) | KDM4E | |
| SCHEMBL5670589 | 0.70 | AHR (0.39) | — | |
| SCHEMBL7711338 | 0.69 | PARP1 (0.52) | ALOX5KDM4EFDPS | |
| SCHEMBL6994006 | 0.69 | ALOX5 (0.36) | ALOX5KDM4EFDPSENPP2 | |
| SCHEMBL6998554 | 0.69 | PARP1 (0.52) | ALOX5KDM4EFDPS | |
| SCHEMBL5670592 | 0.69 | ALOX5 (0.56) | ALOX5 | |
| Hydrochloric Acid SCHEMBL5672533 | 0.69 | AHR (0.38) | — | |
| SCHEMBL7988325 | 0.68 | ALDH1A1 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |