Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866950 | 0.87 | GABRG2 (0.39) | GABRG2GABRB3GABRA3 | |
| SCHEMBL7702504 | 0.86 | GABRG2 (0.39) | GABRG2GABRB3GABRA3 | |
| SCHEMBL6871034 | 0.79 | GABRA1 (0.34) | GABRG2GABRB3GABRA3 | |
| SCHEMBL6866654 | 0.78 | GABRG2 (0.45) | GABRG2GABRB3 | |
| SCHEMBL6862675 | 0.77 | — | — | |
| SCHEMBL6870641 | 0.73 | GABRG2 (0.39) | GABRG2GABRB3 | |
| SCHEMBL7034670 | 0.71 | GABRG2 (0.37) | GABRG2GABRB3GABRA3 | |
| SCHEMBL6872561 | 0.70 | GABRA1 (0.34) | GABRG2GABRB3GABRA3 | |
| SCHEMBL7163927 | 0.69 | EGLN1 (0.33) | GABRG2GABRB3GABRA3 | |
| SCHEMBL6862347 | 0.67 | GABRG2 (0.50) | GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103371-A1 | Substituted imidazo [1,5-a] [1,2,4] triazolo [4,3-d] [1,4] benzodiazepine derivatives | HOFFMANN-LA ROCHE INC. | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103371-A1 | Substituted imidazo [1,5-a] [1,2,4] triazolo [4,3-d] [1,4] benzodiazepine derivatives | GABRA5, GABRA1, GABRA4 | GABRG2 15/4885GABRB3 11/4885GABRA3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.