Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706404 | 0.85 | RAB9A (0.52) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL13623626 | 0.81 | L3MBTL1 (0.55) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL8328384 | 0.75 | HDAC6 (0.45) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL31339222 | 0.73 | KMT2A (0.64) | RAB9AKMT2AMEN1HPGD | |
| SCHEMBL7706403 | 0.72 | RAB9A (0.49) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL8284968 | 0.72 | KMT2A (0.62) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL355357 | 0.72 | ALDH1A1 (0.59) | RAB9AKMT2AL3MBTL1ALDH1A1CASP3 | |
| SCHEMBL8726663 | 0.71 | HPGD (0.38) | RAB9AKMT2AALDH1A1HPGDTSHR | |
| SCHEMBL9314355 | 0.71 | KMT2A (0.66) | RAB9AKMT2AMEN1HPGD | |
| SCHEMBL3717527 | 0.71 | KMT2A (0.72) | RAB9AKMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588357-B1 | Isoxazoles derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |