SCHEMBL7708519

SCHEMBL7708519

CCCCOc1ccc([S+](c2ccccc2)c2ccc(OCCCC)cc2)cc1.O=S(=O)([O-])C(F)(F)C(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
LTA4H P09960 2/20 0.40
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
PTGS2 P35354 1/20 0.37
MMP3 P08254 1/20 0.36
MMP13 P45452 1/20 0.36
MAPK1 P28482 2/20 0.35
RECQL P46063 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
ALOX5 P09917 2/20 0.35
PPARG P37231 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7711590 0.95 CA12 (0.43) TSHRCA12CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL3144088 0.87 TSHR (0.47) TSHRCA12CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL7623512 0.83 LTA4H (0.48) TSHRCA12CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL3740931 0.83 LTA4H (0.48) TSHRCA12CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL7624035 0.83 LTA4H (0.48) TSHRCA12CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL4620123 0.83 LTA4H (0.48) TSHRCA12CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL4620191 0.83 LTA4H (0.48) TSHRCA12CA1CA2CA7
SCHEMBL7708207 0.83 GPR3 (0.34) CA1CA2CA9HTTLMNA
SCHEMBL2440290 0.82 LTA4H (0.47) TSHRCA12CA1CA2CA7
SCHEMBL29745929 0.82 LTA4H (0.47) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed