SCHEMBL7708620

SCHEMBL7708620

COc1ccc(-c2[c]ccc(OC(C)(C)C)c2-c2ccc(OC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.34
ESR2 Q92731 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
APP P05067 1/20 0.33
MAPK1 P28482 2/20 0.31
TP53 P04637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7707636 0.88 ABCB1 (0.32)
SCHEMBL7711577 0.84 MEN1 (0.30) TP53MAPT
SCHEMBL7705600 0.83 SENP1 (0.34) ESR2KDM4E
SCHEMBL7702896 0.81 ALDH1A1 (0.32) ALDH1A1TSHRSMN1; SMN2MAPT
SCHEMBL7708104 0.80 ELANE (0.47) CA2
SCHEMBL7711403 0.78 PTGS2 (0.36) PTGS2ESR2CA12CA1CA2
SCHEMBL7708795 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL7711374 0.76 CA12 (0.44) CA12CA1CA2CA9CA14
SCHEMBL7708308 0.75 CYP3A4 (0.36) TDP1MAPT
SCHEMBL7705593 0.75 TDO2 (0.35) MAPK1TP53ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed