Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylmalonic Acid SCHEMBL107949 | 0.88 | ALPL (0.39) | ALPLPOLBALPGCA2CA4 | |
| Acetic Acid SCHEMBL106040 | 0.84 | CA2 (0.44) | ALPLPOLBALPGCA2CA4 | |
| Methylmalonic Acid SCHEMBL107951 | 0.84 | ALPL (0.37) | ALPLPOLBALPGCA2CA4 | |
| Bicarbonate SCHEMBL105290 | 0.82 | CA2 (0.46) | POLBHPGDCA2CA4CYP2D6 | |
| Bicarbonate SCHEMBL105292 | 0.82 | CA2 (0.46) | POLBHPGDCA2CA4CYP2D6 | |
| Dichloroacetic Acid SCHEMBL105678 | 0.81 | CA2 (0.38) | ALPLPOLBALPGHPGDCA2 | |
| Oxalic Acid SCHEMBL105013 | 0.80 | CA4 (0.44) | POLBHPGDCA2CA4LMNA | |
| SCHEMBL108777 | 0.80 | FFAR1 (0.38) | ALPLPOLBALPGHPGDLMNA | |
| SCHEMBL106865 | 0.80 | ALPL (0.38) | ALPLPOLBALPGHPGDCA2 | |
| Acetic Acid SCHEMBL7788632 | 0.79 | CES2 (0.46) | HPGDCA2CA4LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |