Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.50 |
| ▸ | KLK1 | P06870 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705606 | 0.85 | CSNK1D (0.55) | F2NPC1MEN1KMT2ACSNK1D | |
| SCHEMBL7709116 | 0.84 | ADORA2A (0.48) | ADORA2AKLKB1F2F10NPC1 | |
| SCHEMBL7703131 | 0.82 | ADORA2A (0.46) | ADORA2AKLKB1F2F10NPC1 | |
| SCHEMBL6867628 | 0.81 | ADORA2A (0.60) | ADORA2AKLKB1KLK1F2F10 | |
| SCHEMBL7711803 | 0.81 | F2 (0.47) | ADORA2AF2CSNK1DKDM4E | |
| SCHEMBL7703034 | 0.79 | CSNK1D (0.53) | ADORA2AMEN1KMT2ACSNK1D | |
| SCHEMBL7428533 | 0.77 | ADORA2A (0.60) | ADORA2AF2NPC1MEN1KMT2A | |
| SCHEMBL7708668 | 0.76 | PDE5A (0.49) | ADORA2APDE5ACSNK1DHIF1A | |
| SCHEMBL7438035 | 0.76 | ADORA2A (0.59) | ADORA2AF2NPC1MEN1KMT2A | |
| SCHEMBL6867942 | 0.76 | ADORA2A (0.71) | ADORA2AF2KDM4EF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |