Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 7/20 | 0.53 |
| ▸ | GPR68 | Q15743 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705606 | 0.90 | CSNK1D (0.55) | CSNK1DMAPTEGLN2MEN1POLB | |
| SCHEMBL7705858 | 0.85 | MAPT (0.46) | CSNK1DMAPTMEN1POLBKMT2A | |
| SCHEMBL7708668 | 0.83 | PDE5A (0.49) | CSNK1DMAPTAPPADORA2AADORA1 | |
| SCHEMBL7711803 | 0.82 | F2 (0.47) | CSNK1DGPR68MAPTADORA2AADORA1 | |
| SCHEMBL7708909 | 0.79 | ADORA2A (0.52) | CSNK1DADORA2AMEN1KMT2A | |
| SCHEMBL7703064 | 0.78 | ALDH1A1 (0.45) | CSNK1DMAPTADORA2AADORA1MEN1 | |
| SCHEMBL7431271 | 0.75 | AMY1A (0.50) | CSNK1DMAPTMEN1KMT2A | |
| SCHEMBL6873157 | 0.70 | HPGDS (0.51) | CSNK1DADORA2A | |
| SCHEMBL7708837 | 0.70 | GRM5 (0.52) | ADORA2A | |
| SCHEMBL2555310 | 0.68 | KLKB1 (0.69) | MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |