Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703034 | 0.90 | CSNK1D (0.53) | CSNK1DMAPTPOLBKMT2AMEN1 | |
| SCHEMBL7708668 | 0.90 | PDE5A (0.49) | CSNK1DMAPTTP53 | |
| SCHEMBL7708909 | 0.85 | ADORA2A (0.52) | CSNK1DNPC1F2L3MBTL1KMT2A | |
| SCHEMBL7711803 | 0.84 | F2 (0.47) | CSNK1DMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6873157 | 0.78 | HPGDS (0.51) | CSNK1DALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL7423524 | 0.76 | ALDH1A1 (0.53) | CSNK1DMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7709009 | 0.75 | NPC1 (0.44) | MAPTSMN1; SMN2ALDH1A1HTTNPC1 | |
| SCHEMBL7705858 | 0.75 | MAPT (0.46) | CSNK1DMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7708996 | 0.74 | ADORA3 (0.51) | CSNK1DMAPTALDH1A1POLBKMT2A | |
| SCHEMBL7434291 | 0.74 | ALDH1A1 (0.57) | CSNK1DMAPTSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |