Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714804 | 0.93 | HSD17B10 (0.35) | KDM1AGPR84CCR5 | |
| SCHEMBL7759560 | 0.91 | NOTUM (0.33) | KDM1AGPR84CCR5SMN1; SMN2HTT | |
| SCHEMBL7385061 | 0.85 | LMNA (0.34) | CCR5MEN1NPC1MAPTRAB9A | |
| SCHEMBL7376834 | 0.81 | MAPT (0.38) | SMN1; SMN2HTTMAOAMAOBALDH1A1 | |
| SCHEMBL29001777 | 0.81 | KDM1A (0.40) | KDM1AGPR84CCR5MAOAMAOB | |
| SCHEMBL15821065 | 0.79 | HDAC6 (0.44) | KDM1AGPR84CCR5SMN1; SMN2MAOA | |
| SCHEMBL950483 | 0.79 | KDM1A (0.43) | KDM1AGPR84SMN1; SMN2HTTMAOA | |
| SCHEMBL18599627 | 0.78 | GAA (0.43) | KDM1AGPR84CCR5SMN1; SMN2MAOA | |
| SCHEMBL7714886 | 0.75 | MTNR1A (0.33) | KDM1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7709019 | 0.75 | ALDH1A1 (0.30) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |