Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934288 | 0.75 | PPARG (0.47) | GHSR | |
| SCHEMBL6930581 | 0.74 | ITGB3 (0.47) | SLC7A5 | |
| SCHEMBL6935539 | 0.73 | DPP4 (0.47) | SLC7A5 | |
| SCHEMBL6931543 | 0.73 | CTSL (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ASLC7A5 | |
| SCHEMBL6935590 | 0.72 | ITGA4 (0.48) | ITGB1ITGA4 | |
| SCHEMBL6930981 | 0.72 | ITGB1 (0.39) | ITGB1ITGA4 | |
| SCHEMBL3323628 | 0.67 | HIF1A (0.52) | ALDH1A1SMN1; SMN2EPHX2MEN1KMT2A | |
| SCHEMBL25355736 | 0.67 | SLC7A5 (0.56) | SLC7A5NOS3NOS1NOS2 | |
| SCHEMBL25359079 | 0.67 | SLC7A5 (0.56) | SLC7A5NOS3NOS1NOS2 | |
| SCHEMBL25356665 | 0.67 | SLC7A5 (0.56) | SLC7A5NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362204-B1 | CONTROLLING IMMUNOLOGY; ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS, LTD (GB) | 2002-03-26 | — | — | US | disclosed |