Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709683 | 0.91 | PRMT1 (0.41) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7703835 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7709615 | 0.89 | HTR1A (0.40) | CYP1A2MAPTMEN1KMT2AUSP2 | |
| SCHEMBL8465317 | 0.82 | KMT2A (0.44) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7709607 | 0.81 | KMT2A (0.56) | CYP1A2ALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL7709378 | 0.81 | MEN1 (0.54) | ALDH1A1MAPTNPSR1TDP1PRKDC | |
| SCHEMBL7709360 | 0.79 | KMT2A (0.43) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL7706791 | 0.78 | PRMT1 (0.60) | ALDH1A1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL7706731 | 0.77 | CYP1B1 (0.45) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7703674 | 0.77 | MEN1 (0.41) | CYP1A2ALDH1A1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |