Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 10/20 | 0.34 |
| ▸ | CNR1 | P21554 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574892 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP2C9CYP2C19CNR2 | |
| SCHEMBL7603084 | 0.85 | HPGD (0.37) | ALDH1A1HPGDMAPK8MAPK9TSHR | |
| SCHEMBL7573752 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HPGDMAPK8MAPK9TSHR | |
| SCHEMBL7572306 | 0.71 | THRA (0.43) | ALDH1A1HPGDMAPK8MAPK9CYP2C9 | |
| SCHEMBL7575492 | 0.68 | RARB (0.55) | ALDH1A1HPGDTSHR | |
| SCHEMBL29837403 | 0.66 | HPGD (0.46) | ALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL7050071 | 0.66 | HPGD (0.46) | ALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL7573073 | 0.66 | KDM4E (0.39) | ALDH1A1HPGDCYP2C9CYP2C19MEN1 | |
| SCHEMBL7575694 | 0.66 | CNR2 (0.39) | ALDH1A1HPGDCNR2CNR1 | |
| SCHEMBL7573743 | 0.64 | MAPT (0.41) | ALDH1A1HPGDMAPK8MAPK9CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |