Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715410 | 0.86 | L3MBTL1 (0.39) | THRATHRBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7573040 | 0.80 | THRA (0.39) | THRATHRBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7603084 | 0.79 | HPGD (0.37) | THRBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29837403 | 0.76 | HPGD (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4EGAA | |
| SCHEMBL7050071 | 0.76 | HPGD (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4EGAA | |
| SCHEMBL7573073 | 0.76 | KDM4E (0.39) | THRATHRBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7573752 | 0.76 | ALDH1A1 (0.33) | THRATHRBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL20107668 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDAR | |
| SCHEMBL7580611 | 0.74 | MAPT (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7573743 | 0.74 | MAPT (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |