Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573752 | 0.93 | ALDH1A1 (0.33) | HPGDALDH1A1ALOX5HTR2ATSHR | |
| SCHEMBL7709366 | 0.85 | ALDH1A1 (0.37) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7574892 | 0.83 | ALDH1A1 (0.43) | HPGDALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7572306 | 0.79 | THRA (0.43) | HPGDALDH1A1HTTMAPTTHRB | |
| SCHEMBL7050071 | 0.73 | HPGD (0.46) | HPGDALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL29837403 | 0.73 | HPGD (0.46) | HPGDALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL7573073 | 0.73 | KDM4E (0.39) | HPGDALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL7572253 | 0.71 | CYP3A4 (0.46) | HPGDALDH1A1TSHRMAPTNPC1 | |
| SCHEMBL7573743 | 0.71 | MAPT (0.41) | HPGDALDH1A1TSHRHTTMAPT | |
| SCHEMBL7580611 | 0.71 | MAPT (0.44) | HPGDALDH1A1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |