Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 7/20 | 1.00 |
| ▸ | HCRTR1 | O43613 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710901 | 0.98 | HCRTR2 (1.00) | HCRTR2HCRTR1MAPTKMT2ATSPO | |
| SCHEMBL7701854 | 0.93 | HCRTR2 (0.86) | HCRTR2HCRTR1MAPTKMT2ATSPO | |
| SCHEMBL7707423 | 0.92 | HCRTR2 (1.00) | HCRTR2HCRTR1MAPTKMT2ATSPO | |
| SCHEMBL7709056 | 0.90 | HCRTR2 (0.82) | HCRTR2HCRTR1MAPTKMT2ATSPO | |
| SCHEMBL2594270 | 0.86 | HCRTR2 (0.75) | HCRTR2HCRTR1MAPTKMT2AL3MBTL1 | |
| SCHEMBL7707551 | 0.83 | HCRTR2 (0.71) | HCRTR2HCRTR1MAPTKMT2ATSPO | |
| SCHEMBL7707649 | 0.83 | HCRTR2 (0.82) | HCRTR2HCRTR1MAPTTSPOALDH1A1 | |
| SCHEMBL2588741 | 0.83 | HCRTR2 (0.71) | HCRTR2HCRTR1MAPTKMT2AL3MBTL1 | |
| SCHEMBL2585096 | 0.78 | HCRTR2 (0.74) | HCRTR2HCRTR1MAPTKMT2AL3MBTL1 | |
| SCHEMBL7709292 | 0.77 | HCRTR2 (1.00) | HCRTR2HCRTR1MAPTKMT2ATSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138266-A1 | INDOLIZINE AND IMIDAZOPYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | EVOTEC AG (DE) | 2011-11-10 | — | — | WO | disclosed |