Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864978 | 0.88 | P4HB (0.50) | HNF4AESR1ESR2FFAR1FFAR4 | |
| SCHEMBL15014228 | 0.83 | APP (0.59) | KDM4ECA9 | |
| SCHEMBL19480152 | 0.82 | ERN1 (0.41) | GRM5 | |
| SCHEMBL6743389 | 0.81 | KDM4E (0.41) | ESR1ESR2HSD17B1HSD17B2KDM4E | |
| SCHEMBL200168 | 0.81 | P4HB (0.51) | ESR1ESR2P4HBCA3CA6 | |
| SCHEMBL14307269 | 0.81 | ESR1 (0.44) | ESR1ESR2HSD17B1HSD17B2KDM4E | |
| SCHEMBL29826346 | 0.81 | P4HB (0.51) | ESR1ESR2P4HBCA3CA6 | |
| SCHEMBL24476144 | 0.78 | CYP2A6 (0.41) | KDM4ESHBG | |
| SCHEMBL22615017 | 0.76 | HTR2C (0.41) | KDM4E | |
| SCHEMBL29235680 | 0.76 | SHBG (0.34) | ESR1ESR2HSD17B1HSD17B2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380340-B1 | ACRYLATED ESTER CONTAINING ACETYLENIC BONDS | UNIVERSITY OF DAYTON | 2002-04-30 | — | — | US | disclosed |
| US-6369262-B1 | RIGID-ROD MONOMERS AND POLYMERS ARE PROVIDED FOR USE IN APPLICATIONS SUCH AS RAPID PROTOTYPING, COMPOSITES AND ADHESIVES. | UNIVERSITY OF DAYTON | 2002-04-09 | — | — | US | disclosed |