SCHEMBL200168

SCHEMBL200168

N#Cc1ccc(O)c(F)c1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P4HB P07237 3/20 0.51
AR P10275 1/20 0.49
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CYP19A1 P11511 4/20 0.46
ESR1 P03372 8/20 0.44
ESR2 Q92731 8/20 0.44
MMP3 P08254 1/20 0.41
HSD17B14 Q9BPX1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29826346 1.00 P4HB (0.51) P4HBARCA12CA2CA3
SCHEMBL6864978 0.88 P4HB (0.50) P4HBARCA12CA2CA3
Propionic Acid SCHEMBL10764681 0.84 P4HB (0.48) P4HBARCYP19A1HSD17B14
SCHEMBL9063141 0.84 KIF11 (0.59) P4HBARCA12CA2CA3
SCHEMBL2786052 0.84 KIF11 (0.59) P4HBARCA12CA2CA3
SCHEMBL540294 0.82 P4HB (0.51) P4HBARCA12CA2CA3
SCHEMBL22749362 0.82 P4HB (0.40) P4HBARCYP19A1ESR1ESR2
SCHEMBL7710176 0.81 HNF4A (0.42) P4HBCA3CA6CA9CA14
4-Cyanophenol SCHEMBL28162196 0.81 CA3 (0.57) P4HBARCA12CA2CA3
SCHEMBL229147 0.78 EGLN2 (0.44) CA12CA2CA3CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563606-B Synthesis method of (R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy ] propionic acid 湖南速博生物技术有限公司 2022-06-21 CN claimed
CN-109212110-B Gas chromatography-mass spectrometry combined method for measuring three trace monohalogenated hydroxyl benzonitrile in river water 丁立平 2021-05-11 CN claimed
CN-110563606-A Synthesis method of (R) -2- [4- (4-cyano-2-fluorophenoxy) phenoxy ] propionic acid 湖南速博生物技术有限公司 2019-12-13 CN claimed
CN-110283173-A A kind of imide analog compounds and its preparation method and application 济南大学 2019-09-27 CN claimed
CN-108774155-A A kind of preparation method of the fluoro- 4- cyanophenols of 3- 河北凡克新材料有限公司 2018-11-09 CN claimed
US-8945887-B2 Whole cell biocatalyst ZYRUS BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE I KG (DE) 2015-02-03 US claimed
US-20130011890-A1 WHOLE CELL BIOCATALYST ZYRUS BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE I KG (DE) 2013-01-10 US claimed
EP-2501807-A2 WHOLE CELL BIOCATALYST ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG (DE) 2012-09-26 EP claimed
EP-2338987-A1 Whole cell biocatalyst ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG (DE) 2011-06-29 EP claimed
WO-2011057820-A2 WHOLE CELL BIOCATALYST ZYRUS BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE I KG (DE) 2011-05-19 WO claimed
US-20100258033-A1 WOOD ADHESIVE AND METHOD OF PREPARING THEREOF YANG GUANG 2010-10-14 US claimed
EP-2236578-A1 A NEW LUMBER ADHESIVE AND THE PREPARATION THEREOF Yang, Guang (CN) 2010-10-06 EP claimed
CN-122036560-A Radioactive medical isotope18F-labeled norepinephrine analogue as well as preparation method and application thereof 中国医学科学院阜外医院 2026-05-15 CN disclosed
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 US disclosed
US-12595249-B2 Aryl ether-substituted heterocyclic compounds as glpir agonists MINDRANK AI LTD. (CN) 2026-04-07 US disclosed
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-04-07 US disclosed
EP-0220254-A1 BENZONITRILES. MERCK PATENT GMBH (DE) 1987-05-06 EP disclosed
EP-0219143-A1 Synergistic herbicidal compositions and methods of use STAUFFER CHEMICAL COMPANY (US) 1987-04-22 EP disclosed
WO-1986006372-A1 BENZONITRILE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-11-06 WO disclosed
WO-1985004874-A1 ANISOTROPIC COMPOUNDS AND LIQUID CRYSTAL MIXTURES THEREWITH MERCK PATENT GMBH (DE) 1985-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595249-B2 Aryl ether-substituted heterocyclic compounds as glpir agonists GLP1R, GIPR, GCGR P4HB 3397/4885AR 207/4885CA12 3247/4885
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics CLIC1, CBR3, CBR1 P4HB 396/4885AR 3082/4885CA12 3573/4885
US-12617762-B2 Carboxy derivatives with antiinflamatory properties CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 P4HB 1848/4885AR 3195/4885CA12 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.