Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528985 | 0.90 | GAA (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2097245 | 0.85 | ERN1 (0.40) | KMT2AMAPTALDH1A1ERN1RAPGEF4 | |
| SCHEMBL22550906 | 0.73 | RAPGEF4 (0.35) | ERN1RAPGEF4 | |
| SCHEMBL16240458 | 0.72 | ALDH1A1 (0.37) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7710208 | 0.72 | KMT2A (0.46) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5793592 | 0.71 | ALDH1A1 (0.57) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6036195 | 0.69 | ALDH1A1 (0.56) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9249346 | 0.68 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL29921076 | 0.68 | ERN1 (0.42) | KMT2AMAPTALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL6556132 | 0.68 | ERN1 (0.42) | KMT2AMAPTALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | disclosed |