Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710467 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDRAB9AMAPTNPC1 | |
| SCHEMBL29248099 | 0.84 | P4HA1 (0.46) | SMN1; SMN2HPGDRAB9AMAPTNPC1 | |
| SCHEMBL29114321 | 0.84 | P4HA1 (0.46) | SMN1; SMN2HPGDRAB9AMAPTNPC1 | |
| SCHEMBL18614535 | 0.80 | DGAT1 (0.54) | SMN1; SMN2HPGDRAB9AMAPTNPC1 | |
| SCHEMBL18614534 | 0.80 | DGAT1 (0.54) | SMN1; SMN2HPGDRAB9AMAPTNPC1 | |
| SCHEMBL21431824 | 0.73 | HCAR2 (0.47) | SMN1; SMN2HPGDRAB9ANPC1NPSR1 | |
| SCHEMBL21408786 | 0.73 | HCAR2 (0.47) | SMN1; SMN2HPGDRAB9ANPC1NPSR1 | |
| SCHEMBL11259705 | 0.72 | ALDH1A1 (0.49) | RAB9AMAPTNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL11259703 | 0.72 | ALDH1A1 (0.49) | RAB9AMAPTNPSR1HSD17B10ALDH1A1 | |
| SCHEMBL4901313 | 0.72 | CYP1A2 (0.49) | SMN1; SMN2HPGDRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362191-B1 | ANTIBIOTICS | ZENECA LTD. (GB) | 2002-03-26 | — | — | US | disclosed |
| EP-1007525-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999011642-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-11 | — | — | WO | disclosed |