Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.34 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735327 | 0.83 | FFAR1 (0.43) | ACACB | |
| SCHEMBL7711978 | 0.81 | PTGS1 (0.36) | ACACBPTGS2PTGS1MT-CO1MT-CO2 | |
| SCHEMBL5738032 | 0.79 | PTGER4 (0.40) | ACACBHTTKMT2A | |
| SCHEMBL6757126 | 0.75 | HTR5A (0.32) | — | |
| SCHEMBL4516381 | 0.75 | ACACB (0.38) | ACACBPTGS2 | |
| SCHEMBL7711974 | 0.74 | SLC6A2 (0.40) | ACACBPTGS2PTGS1MT-CO1MT-CO2 | |
| SCHEMBL5737780 | 0.72 | ACACB (0.40) | ACACBHTTKMT2A | |
| SCHEMBL6427623 | 0.69 | TBXAS1 (0.44) | ACACB | |
| SCHEMBL5737546 | 0.68 | ALDH1A1 (0.36) | KMT2A | |
| SCHEMBL4518175 | 0.67 | CYP26A1 (0.34) | ACACBPTGS2PTGS1MT-CO1MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369225-B1 | ENZYME INHIBITORS | ALLERGAN SALES, INC. | 2002-04-09 | — | — | US | disclosed |