Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706437 | 0.68 | KDM4E (0.35) | ALDH1A1HSD17B10HPGDKDM4ECASP1 | |
| SCHEMBL7712463 | 0.68 | L3MBTL1 (0.70) | ALDH1A1HSD17B10HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL14713173 | 0.62 | HSD17B10 (0.40) | ALDH1A1HSD17B10HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL1404275 | 0.61 | CHRM2 (0.46) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL15934206 | 0.60 | HSD17B10 (0.45) | ALDH1A1HSD17B10HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11323139 | 0.60 | L3MBTL1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPTTDP1 | |
| SCHEMBL31727996 | 0.58 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL20692482 | 0.58 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL1498698 | 0.57 | PNP (0.44) | ALDH1A1HPGDKDM4EMAPTTDP1 | |
| SCHEMBL11930694 | 0.57 | KDM4E (0.38) | ALDH1A1KDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |