Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16497259 | 0.69 | PKM (0.32) | KDM4ENOS3NOS1NOS2 | |
| SCHEMBL11930694 | 0.65 | KDM4E (0.38) | KDM4ENPSR1DPP4ALDH1A1 | |
| SCHEMBL16010498 | 0.61 | BRD4 (0.36) | KDM4EALDH1A1HPGDHSD17B10NOS3 | |
| SCHEMBL11916282 | 0.61 | ALDH1A1 (0.33) | KDM4ENPSR1DPP4ALDH1A1HPGD | |
| SCHEMBL24572157 | 0.58 | KDM4E (0.58) | KDM4ENPSR1DPP4ALDH1A1HSD17B10 | |
| SCHEMBL5410862 | 0.58 | ADORA2B (0.45) | KDM4ENPSR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL19697586 | 0.58 | KDM4E (0.40) | KDM4EHPGDHSD17B10 | |
| SCHEMBL9505954 | 0.57 | KDM4E (0.35) | KDM4ENPSR1DPP4ALDH1A1HPGD | |
| SCHEMBL21565452 | 0.57 | NPSR1 (0.49) | KDM4ENPSR1ALDH1A1HSD17B10 | |
| SCHEMBL12869079 | 0.57 | NOS3 (0.33) | NPSR1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |