Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | STAT1 | P42224 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706472 | 0.79 | GAA (0.67) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL7819172 | 0.75 | TP53 (0.64) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL7706435 | 0.71 | TSHR (0.51) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL23521306 | 0.68 | PI4KB (0.58) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL7256671 | 0.68 | KMT2A (0.52) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL7712466 | 0.68 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL17926587 | 0.68 | L3MBTL1 (0.74) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL17926547 | 0.67 | KCNN3 (0.68) | L3MBTL1ALDH1A1TP53HPGDMAPT | |
| SCHEMBL25986235 | 0.66 | ADCY1 (0.68) | — | |
| SCHEMBL20595556 | 0.66 | HSD17B10 (0.49) | L3MBTL1ALDH1A1TP53HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |