Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781095 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL11600743 | 0.84 | MAPT (0.48) | ALDH1A1LMNAHSD17B10MAPTTP53 | |
| SCHEMBL7720050 | 0.81 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL6782412 | 0.80 | LMNA (0.45) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL27475763 | 0.79 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL6774233 | 0.79 | MAPT (0.39) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL6774973 | 0.77 | RAB9A (0.43) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7619436 | 0.76 | NSD2 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL11601588 | 0.75 | MAPT (0.46) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| SCHEMBL6774510 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384014-B1 | ANTIBIOTICS AS BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2002-05-07 | — | — | US | disclosed |