Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710548 | 0.82 | HCRTR2 (0.41) | KDM5A | |
| SCHEMBL7703480 | 0.82 | HCRTR2 (0.41) | KDM5A | |
| SCHEMBL2563182 | 0.79 | NPC1 (0.46) | KDM5AHDAC4PDE4APDE4BPDE4C | |
| SCHEMBL2563184 | 0.79 | NPC1 (0.46) | KDM5AHDAC4PDE4APDE4BPDE4C | |
| SCHEMBL29765569 | 0.76 | — | — | |
| SCHEMBL16060787 | 0.76 | — | — | |
| SCHEMBL7707988 | 0.75 | CYP11B2 (0.50) | — | |
| SCHEMBL7704805 | 0.75 | HCRTR2 (0.38) | HDAC4 | |
| SCHEMBL2563797 | 0.74 | P2RX7 (0.44) | KDM5AHDAC4 | |
| SCHEMBL2560138 | 0.74 | GAA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011131596-A1 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES AS VASOPRESSIN V1A RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-10-27 | — | — | WO | disclosed |