Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718415 | 1.00 | KDM4D (0.33) | KDM4DMAPTFPR2SCN9ACKS1B | |
| SCHEMBL7718967 | 1.00 | KDM4D (0.33) | KDM4DMAPTFPR2SCN9ACKS1B | |
| SCHEMBL7719303 | 0.86 | SCN9A (0.38) | SCN9A | |
| SCHEMBL7717555 | 0.86 | SCN9A (0.38) | SCN9A | |
| SCHEMBL7721427 | 0.86 | MTNR1B (0.36) | SCN9A | |
| SCHEMBL7709306 | 0.86 | MTNR1B (0.36) | SCN9A | |
| SCHEMBL7718518 | 0.86 | MTNR1B (0.36) | SCN9A | |
| SCHEMBL12009173 | 0.81 | KDM4D (0.42) | KDM4DMAPTFPR2 | |
| SCHEMBL7713116 | 0.74 | ACHE (0.35) | KDM4DCKS1BSKP1SKP2 | |
| SCHEMBL7715083 | 0.74 | KMT2A (0.34) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |