Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.31 |
| ▸ | SKP1 | P63208 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713116 | 0.79 | ACHE (0.35) | KMT2AL3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL7718518 | 0.78 | MTNR1B (0.36) | KMT2AL3MBTL1DRD2NPY1R | |
| SCHEMBL7709306 | 0.78 | MTNR1B (0.36) | KMT2AL3MBTL1DRD2NPY1R | |
| SCHEMBL7721427 | 0.78 | MTNR1B (0.36) | KMT2AL3MBTL1DRD2NPY1R | |
| SCHEMBL7719303 | 0.77 | SCN9A (0.38) | DRD2NPY1R | |
| SCHEMBL7717555 | 0.77 | SCN9A (0.38) | DRD2NPY1R | |
| SCHEMBL7718415 | 0.74 | KDM4D (0.33) | CKS1BSKP1SKP2 | |
| SCHEMBL7718967 | 0.74 | KDM4D (0.33) | CKS1BSKP1SKP2 | |
| SCHEMBL7713113 | 0.74 | KDM4D (0.33) | CKS1BSKP1SKP2 | |
| SCHEMBL7397427 | 0.66 | KMT2A (0.40) | KMT2AL3MBTL1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |