SCHEMBL771326

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6396188	0.80	FLT3 (0.54)	KDM4EALDH1A1MAPTHPGDSMN1; SMN2
	SCHEMBL30366356	0.75	FAAH (0.44)	KDM4EALDH1A1MAPTCYP19A1NPSR1
	SCHEMBL27437769	0.74	KDR (0.56)	KDRAURKACHEK1SLC22A12KDM4E
	SCHEMBL28906323	0.73	KDR (0.54)	KDRAURKACHEK1SLC22A12KDM4E
	SCHEMBL31310116	0.73	KDR (0.54)	KDRAURKACHEK1KDM4EMEN1
	SCHEMBL11365957	0.73	KDR (0.54)	KDRAURKACHEK1SLC22A12KDM4E
	SCHEMBL2860216	0.73	KDR (0.54)	KDRAURKACHEK1KDM4EMEN1
	SCHEMBL10118094	0.72	ALDH1A1 (0.54)	KDM4EALDH1A1KMT2ALMNAPOLB
	SCHEMBL4623053	0.71	ESR1 (0.53)	KDRAURKACHEK1SLC22A12KDM4E
	SCHEMBL7062756	0.70	SLC22A12 (0.57)	KDRAURKACHEK1SLC22A12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.