SCHEMBL2628191

SCHEMBL2628191

O=C(O)Cc1ccc(OCC[18F])cc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 1/20 0.55
TBXAS1 P24557 1/20 0.52
FFAR1 O14842 3/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MMP2 P08253 2/20 0.50
APP P05067 2/20 0.50
MMP1 P03956 1/20 0.50
MMP3 P08254 1/20 0.50
MMP9 P14780 1/20 0.50
MMP12 P39900 1/20 0.50
MMP13 P45452 1/20 0.50
MMP14 P50281 1/20 0.50
LTB4R Q15722 2/20 0.49
LTB4R2 Q9NPC1 2/20 0.49
ALOX15 P16050 1/20 0.49
CA2 P00918 1/20 0.48
CAMK2A Q9UQM7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2628195 1.00 PLA2G4B (0.55) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA
SCHEMBL11683055 0.88 PLA2G4B (0.61) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA
SCHEMBL7713619 0.87 PLA2G4B (0.56) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA
SCHEMBL11684213 0.86 PLA2G4B (0.69) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA
SCHEMBL1162418 0.85 PLA2G4B (0.59) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA
SCHEMBL926518 0.85 LTA4H (0.58) PLA2G4BTBXAS1ALDH1A1LMNALTB4R
SCHEMBL10728695 0.85 PLA2G4B (0.59) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA
SCHEMBL11209134 0.85 CA2 (0.52) PLA2G4BTBXAS1FFAR1LMNALTB4R
SCHEMBL2628204 0.84 ALDH1A1 (0.58) ALDH1A1LMNAL3MBTL1APP
SCHEMBL11596764 0.84 NR4A2 (0.54) PLA2G4BTBXAS1FFAR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120100073-A1 PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE WASHINGTON UNIVERSITY (US) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100073-A1 PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE LIPC, PNLIP, FFAR1 PLA2G4B 330/4885TBXAS1 143/4885FFAR1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.