Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714642 | 0.87 | CYP2A6 (0.46) | HTR7CYP2A6MAOAMAOBSIGMAR1 | |
| SCHEMBL599314 | 0.78 | CYP19A1 (0.54) | MAOAMAOBSIGMAR1CYP19A1 | |
| SCHEMBL7712799 | 0.77 | CYP2A6 (0.50) | HTR7CYP2A6MAOAMAOBCES1 | |
| SCHEMBL7712791 | 0.76 | DRD2 (0.39) | HTR7DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9407838 | 0.76 | HTR1A (0.51) | HTR7DRD2 | |
| SCHEMBL5608451 | 0.76 | CYP19A1 (0.59) | SIGMAR1HTR2CACHECYP19A1 | |
| SCHEMBL27342980 | 0.75 | SIGMAR1 (0.50) | HTR7CYP2A6MAOAMAOBSIGMAR1 | |
| SCHEMBL7714801 | 0.74 | CYP2A6 (0.43) | HTR7CYP2A6MAOAMAOBSIGMAR1 | |
| SCHEMBL10568326 | 0.74 | PLAU (0.60) | HTR7CYP2A6MAOAMAOBCES1 | |
| SCHEMBL10568813 | 0.74 | MAOA (0.50) | HTR7CYP2A6MAOAMAOBCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |