Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARG | P13631 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053853 | 0.82 | ALDH1A1 (0.42) | RARARARBRARGAKR1B1 | |
| SCHEMBL4373634 | 0.77 | LMNA (0.42) | HTT | |
| SCHEMBL9054289 | 0.74 | MAPT (0.41) | AKR1B1 | |
| SCHEMBL8523001 | 0.74 | RARB (0.55) | RARARARBRARG | |
| SCHEMBL7141574 | 0.73 | RARB (0.74) | RARARARBRARG | |
| SCHEMBL8776331 | 0.73 | RARB (0.42) | RARARARBRARGAKR1B1 | |
| SCHEMBL1391371 | 0.73 | RARB (0.53) | RARARARBRARG | |
| Hydrochloric Acid SCHEMBL21750681 | 0.73 | MAPT (0.44) | AKR1B1 | |
| SCHEMBL8101913 | 0.72 | RARB (0.53) | RARARARBRARGAKR1B1 | |
| SCHEMBL4421853 | 0.72 | KDM4E (0.50) | RARARARBRARGAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368608-B1 | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHE DERMATOLOGIQUES GALDERMA (C.I.R.D.) (FR) | 2002-04-09 | — | — | US | disclosed |
| US-6162445-A | Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5716624-A | USEFUL FOR TREATING DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, OPTHALMOLOGICAL DISORDERS, AS WELL AS MAMMALIAN SKIN AND HAIR CONDITIONS/DISORDERS | C.I.R.D. GALDERMA (FR) | 1998-02-10 | — | — | US | disclosed |