Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.42 |
| ▸ | RARG | P13631 | 10/20 | 0.42 |
| ▸ | RARA | P10276 | 9/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | USP9X | Q93008 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458478 | 0.83 | RXRA (0.54) | RARBRARGRARARXRAPTGS1 | |
| SCHEMBL10356206 | 0.74 | RXRA (0.64) | RARBRARGRARARXRACYP1A2 | |
| SCHEMBL7141574 | 0.74 | RARB (0.74) | RARBRARGRARARXRACYP1A2 | |
| SCHEMBL7714819 | 0.73 | RARA (0.39) | RARBRARGRARAAKR1B1 | |
| SCHEMBL8523001 | 0.72 | RARB (0.55) | RARBRARGRARARXRACYP1A2 | |
| SCHEMBL9053853 | 0.71 | ALDH1A1 (0.42) | RARBRARGRARAAKR1B1 | |
| SCHEMBL4421853 | 0.70 | KDM4E (0.50) | RARBRARGRARARXRAAKR1B1 | |
| SCHEMBL8101913 | 0.70 | RARB (0.53) | RARBRARGRARARXRAAKR1B1 | |
| SCHEMBL6143646 | 0.69 | P4HTM (0.39) | PTGS1PTGS2AKR1B1 | |
| SCHEMBL8776329 | 0.69 | RARA (0.57) | RARBRARGRARARXRAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |