Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 15/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714833 | 1.00 | KDM4D (0.43) | KDM4DIGF1RSTSCYP3A4 | |
| SCHEMBL7714059 | 0.91 | KDM4D (0.45) | KDM4D | |
| SCHEMBL7714056 | 0.91 | KDM4D (0.45) | KDM4D | |
| SCHEMBL7714015 | 0.85 | SLC6A5 (0.41) | — | |
| SCHEMBL7714012 | 0.85 | SLC6A5 (0.41) | — | |
| SCHEMBL4557152 | 0.83 | KCNA3 (0.43) | KDM4D | |
| Trifluoroacetic Acid SCHEMBL7713229 | 0.73 | DPP4 (0.48) | — | |
| SCHEMBL7718989 | 0.72 | NPY1R (0.45) | — | |
| SCHEMBL12527649 | 0.72 | HDAC1 (0.46) | STS | |
| SCHEMBL7718985 | 0.72 | NPY1R (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |