Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714012 | 1.00 | SLC6A5 (0.41) | SLC6A5CHRM3XIAPPKMGHSR | |
| SCHEMBL7714833 | 0.85 | KDM4D (0.43) | — | |
| SCHEMBL7714834 | 0.85 | KDM4D (0.43) | — | |
| SCHEMBL7714059 | 0.81 | KDM4D (0.45) | — | |
| SCHEMBL7714056 | 0.81 | KDM4D (0.45) | — | |
| SCHEMBL4557152 | 0.80 | KCNA3 (0.43) | KMT2AL3MBTL1 | |
| SCHEMBL7714189 | 0.79 | KMT2A (0.46) | KMT2AL3MBTL1 | |
| SCHEMBL7714192 | 0.79 | KMT2A (0.46) | KMT2AL3MBTL1 | |
| SCHEMBL7714010 | 0.74 | SLC16A3 (0.40) | XIAPKMT2AL3MBTL1S1PR1S1PR5 | |
| SCHEMBL5569337 | 0.74 | MMP1 (0.54) | KMT2AL3MBTL1YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |