SCHEMBL2561871

SCHEMBL2561871

O=Cn1ccc(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.50
DDB1 Q16531 1/20 0.45
PKM P14618 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
DUT P33316 4/20 0.33
SLC28A1 O00337 1/20 0.33
SLC28A2 O43868 1/20 0.33
SLC29A1 Q99808 1/20 0.33
SLC28A3 Q9HAS3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7984568 0.81 CRBN (0.45) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL28242393 0.80 CRBN (0.54) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7204552 0.80 CRBN (0.48) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7715133 0.78 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL8988103 0.78 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL7715134 0.78 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL10694738 0.78 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL3414870 0.78 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1
SCHEMBL19348252 0.74 CRBN (0.43) CRBNDDB1L3MBTL1ALDH1A1LMNA
SCHEMBL5705360 0.70 CRBN (0.47) CRBNDDB1PKML3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181147-B Preparation method of C4 '-trifluoromethylthio modified nucleoside and C4' -trifluoromethylthio modified nucleic acid 南开大学 2024-04-02 CN claimed
CN-117512078-A Single primer to double primer amplicon conversion 西格马-奥尔德里奇有限责任公司 2024-02-06 CN claimed
CN-109804083-B Single primer to double primer amplicon conversion 西格马-奥尔德里奇有限责任公司 2023-11-03 CN claimed
US-20220315972-A1 SINGLE PRIMER TO DUAL PRIMER AMPLICON SWITCHING SIGMA ALDRICH CO LLC (US) 2022-10-06 US claimed
US-11390913-B2 Single primer to dual primer amplicon switching SIGMA-ALDRICH CO. LLC (US) 2022-07-19 US claimed
US-12595506-B2 Compositions and methods for analyzing modified nucleotides NEW ENGLAND BIOLABS, INC. (US) 2026-04-07 US disclosed
US-12571024-B2 Methods and compositions relating to covalently closed nucleic acids Twist Bioscience Corporation (US) 2026-03-10 US disclosed
EP-3971201-B1 CELL CULTURING SCAFFOLD MATERIAL AND CELL CULTURING CONTAINER SEKISUI CHEMICAL CO LTD (JP) 2026-01-28 EP disclosed
EP-3971200-B1 CELL CULTURING SCAFFOLDING MATERIAL AND CELL CULTURING VESSEL SEKISUI CHEMICAL CO LTD (JP) 2026-01-21 EP disclosed
EP-4664304-A2 NUCLEIC ACID BASED DATA STORAGE Atlas Data Storage, Inc. (US) 2025-12-17 EP disclosed
US-12460167-B2 Scaffold material for cell culture and cell culture container SEKISUI CHEMICAL CO., LTD. (JP) 2025-11-04 US disclosed
EP-3516528-B1 NUCLEIC ACID BASED DATA STORAGE ATLAS DATA STORAGE INC (US) 2025-10-15 EP disclosed
US-11263354-B2 Nucleic acid based data storage Twist Bioscience Corporation (US) 2022-03-01 US disclosed
EP-3950925-A1 CELL CULTURE SCAFFOLD MATERIAL, CELL CULTURE VESSEL, CELL CULTURE CARRIER, CELL CULTURE FIBER AND CELL CULTURE METHOD SEKISUI CHEMICAL CO., LTD. (JP) 2022-02-09 EP disclosed
WO-2011132017-A1 PYRIDO[3,4-D]PYRIMIDINYL ACETAMIDE DERIVATIVES AS TRPA1 MODULATORS GLENMARK PHARMACEUTICALS S.A. (CH) 2011-10-27 WO disclosed
WO-2010125469-A1 PYRIMIDINEDIONE-FUSED HETEROCYCLIC COMPOUNDS AS TRPA1 MODULATORS GLENMARK PHARMACEUTICALS, S.A. (CH) 2010-11-04 WO disclosed
US-7534796-B2 Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor WYETH (US) 2009-05-19 US disclosed
WO-2006135763-A2 INHIBITORS OF DNA REPAIR ENZYMES AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2006-12-21 WO disclosed
US-20060189617-A1 Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor WYETH (US) 2006-08-24 US disclosed
WO-2002048320-A2 CRYSTAL STRUCTURES OF RETAINING GLYCOSYLTRANSFERASES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571024-B2 Methods and compositions relating to covalently closed nucleic acids UNG, OGG1, RNGTT CRBN 3348/4885DDB1 217/4885PKM 3768/4885
US-20060189617-A1 Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor GNRHR, PRLHR, FSHR CRBN 1958/4885DDB1 3093/4885PKM 3753/4885
US-12595506-B2 Compositions and methods for analyzing modified nucleotides UNG, RNMT, NT5C3B CRBN 2952/4885DDB1 480/4885PKM 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.