Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.31 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414870 | 0.79 | CRBN (0.47) | CRBNDDB1PKMDUTL3MBTL1 | |
| SCHEMBL7715133 | 0.79 | CRBN (0.47) | CRBNDDB1PKMDUTL3MBTL1 | |
| SCHEMBL9486303 | 0.79 | CRBN (0.47) | CRBNDDB1PKMDUTSLC28A1 | |
| SCHEMBL9486307 | 0.79 | CRBN (0.47) | CRBNDDB1PKMDUTSLC28A1 | |
| SCHEMBL2561871 | 0.78 | CRBN (0.50) | CRBNDDB1PKMDUTL3MBTL1 | |
| SCHEMBL7984568 | 0.78 | CRBN (0.45) | CRBNDDB1PKMDUTL3MBTL1 | |
| SCHEMBL7204552 | 0.77 | CRBN (0.48) | CRBNDDB1PKMDUTL3MBTL1 | |
| SCHEMBL19348252 | 0.75 | CRBN (0.43) | CRBNDDB1DUTL3MBTL1ALDH1A1 | |
| SCHEMBL19052857 | 0.68 | CRBN (0.40) | CRBNDDB1PKMDUTALDH1A1 | |
| SCHEMBL8790967 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719271-A1 | 5-(1-FLUORO-VINYL)-1H-PYRIMIDINE-2,4-DIONE DERIVATIVES USEFUL AS ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007917-A1 | 5-(1-FLUORO-VINYL)-1H-PYRIMIDINE-2,4-DIONE DERIVATIVES USEFUL AS ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-03-23 | — | — | WO | disclosed |